NEUROPEPTIDE Y: PHYSIOLOGICAL ROLE AND CLINICAL VALUE

  • А П Листопадова Saint-Petersburg State Pediatric Medical University, 194100, Saint-Petersburg, Litovskaya str., 2
  • Ю В Петренко Saint-Petersburg State Pediatric Medical University, 194100, Saint-Petersburg, Litovskaya str., 2
Keywords:
нейропептид Y аппетит ожирение моторика бронхов моторика желудочно-кишечного тракта рецепторы NPY neuropeptide Y appetite obesity motor bronchus gastrointestinal motility NPY receptors

Abstract

A review of the literature devoted to the neuropeptide Y is given. This peptide is widely distributed in the human body and participates in various physiological processes. Since its discovery, the effect of NPY on the regulation of metabolism, appetite, its relation to food intake and obesity, pain syndrome, and the pathology of the cardiovascular system has been proved. However, the mechanisms of peptide influence on bronchial motility in bronchial asthma, on the motility of the gastrointestinal tract have not been fully studied. The study of modulators of NPY receptors deserves special attention to develop a new pathogenetic approach for the treatment of various diseases.

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