INFLUENCE FUNGAL SENSITIZATION ON THE DEVELOPMENT OF RESPIRATORY ALLERGIES IN CHILDREN

  • О Н Варламова Saint-Petersburg State Pediatric Medical University, 194100, Saint-Petersburg, Litovskaya str., 2
  • Е А Дементьева Saint-Petersburg State Pediatric Medical University, 194100, Saint-Petersburg, Litovskaya str., 2
  • О П Гурина Saint-Petersburg State Pediatric Medical University, 194100, Saint-Petersburg, Litovskaya str., 2
  • А Е Блинов Saint-Petersburg State Pediatric Medical University, 194100, Saint-Petersburg, Litovskaya str., 2
  • А А Степанова Saint-Petersburg State Pediatric Medical University, 194100, Saint-Petersburg, Litovskaya str., 2
Keywords:
аллергодиагностика Rhizopus nigricans Cladosporium herbarum Aspergillus niger Aspergillus flavus Aspergillus awamori Alternaria tenuis IgE респираторный аллергоз атопическая бронхиальная астма allergodiagnostics respiratory allergosis atopic bronchial asthma

Abstract

Allergodiagnostics was carried out in children at risk for the development of fungal sensitization with a diagnosis of respiratory allergosis. The diagnostics was carried out by enzyme immunoassay using a pediatric panel and biotinylating fungal allergens (Rhizopus nigricans, Cladosporium herbarum, Aspergillus niger, Aspergillus flavus, Aspergillus awamory and Alternaria tenuis). As a result of the diagnosis, it was found that mold allergens are a causally significant factor in the development of respiratory allergy, including bronchial asthma, in children at risk. All children with atopic asthma have polyvalent sensitization. Mold allergens should be considered in the preparation of the diagnostic panel for children at risk. Drug therapy of respiratory allergies in children with mycogenic sensitization should be accompanied by measures to eliminate causally significant allergens from the domestic environment. 

Most read articles by the same author(s)